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Induced Prion Protein Controls Immune-Activated Retroviruses in the Mouse Spleen

The prion protein (PrP) is crucially involved in transmissible spongiform encephalopathies (TSE), but neither its exact role in disease nor its physiological function are known. Here we show for mice, using histological, immunochemical and PCR-based methods, that stimulation of innate resistance was...

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Detalles Bibliográficos
Autores principales: Lötscher, Marius, Recher, Mike, Lang, Karl S., Navarini, Alexander, Hunziker, Lukas, Santimaria, Roger, Glatzel, Markus, Schwarz, Petra, Böni, Jürg, Zinkernagel, Rolf M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063463/
https://www.ncbi.nlm.nih.gov/pubmed/17987132
http://dx.doi.org/10.1371/journal.pone.0001158