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Bcl-2 differentially regulates Ca(2+) signals according to the strength of T cell receptor activation
To investigate the effect of Bcl-2 on Ca(2+) signaling in T cells, we continuously monitored Ca(2+) concentration in Bcl-2–positive and –negative clones of the WEHI7.2 T cell line after T cell receptor (TCR) activation by anti-CD3 antibody. In Bcl-2–negative cells, high concentrations of anti-CD3 an...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063540/ https://www.ncbi.nlm.nih.gov/pubmed/16391001 http://dx.doi.org/10.1083/jcb.200506189 |