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Bcl-2 differentially regulates Ca(2+) signals according to the strength of T cell receptor activation

To investigate the effect of Bcl-2 on Ca(2+) signaling in T cells, we continuously monitored Ca(2+) concentration in Bcl-2–positive and –negative clones of the WEHI7.2 T cell line after T cell receptor (TCR) activation by anti-CD3 antibody. In Bcl-2–negative cells, high concentrations of anti-CD3 an...

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Detalles Bibliográficos
Autores principales:	Zhong, Fei, Davis, Michael C., McColl, Karen S., Distelhorst, Clark W.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063540/ https://www.ncbi.nlm.nih.gov/pubmed/16391001 http://dx.doi.org/10.1083/jcb.200506189

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