CIB1 is an endogenous inhibitor of agonist-induced integrin αIIbβ3 activation

In response to agonist stimulation, the αIIbβ3 integrin on platelets is converted to an active conformation that binds fibrinogen and mediates platelet aggregation. This process contributes to both normal hemostasis and thrombosis. Activation of αIIbβ3 is believed to occur in part via engagement of...

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Detalles Bibliográficos
Autores principales: Yuan, Weiping, Leisner, Tina M., McFadden, Andrew W., Wang, Zhengyan, Larson, Mark K., Clark, Shantres, Boudignon-Proudhon, Christel, Lam, Stephen C.-T., Parise, Leslie V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063547/
https://www.ncbi.nlm.nih.gov/pubmed/16418530
http://dx.doi.org/10.1083/jcb.200505131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063547/
https://www.ncbi.nlm.nih.gov/pubmed/16418530
http://dx.doi.org/10.1083/jcb.200505131

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