Coregulated human globin genes are frequently in spatial proximity when active

The organization of genes within the nucleus may influence transcription. We have analyzed the nuclear positioning of the coordinately regulated α- and β-globin genes and show that the gene-dense chromatin surrounding the human α-globin genes is frequently decondensed, independent of transcription....

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Detalles Bibliográficos
Autores principales: Brown, Jill M., Leach, Joanne, Reittie, Joyce E., Atzberger, Ann, Lee-Prudhoe, Jane, Wood, William G., Higgs, Douglas R., Iborra, Francisco J., Buckle, Veronica J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063548/
https://www.ncbi.nlm.nih.gov/pubmed/16418531
http://dx.doi.org/10.1083/jcb.200507073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063548/
https://www.ncbi.nlm.nih.gov/pubmed/16418531
http://dx.doi.org/10.1083/jcb.200507073

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