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The Png1–Rad23 complex regulates glycoprotein turnover

Misfolded proteins in the endoplasmic reticulum (ER) are destroyed by a pathway termed ER-associated protein degradation (ERAD). Glycans are often removed from glycosylated ERAD substrates in the cytosol before substrate degradation, which maintains the efficiency of the proteasome. Png1, a deglycos...

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Detalles Bibliográficos
Autores principales: Kim, Ikjin, Ahn, Jungmi, Liu, Chang, Tanabe, Kaori, Apodaca, Jennifer, Suzuki, Tadashi, Rao, Hai
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063551/
https://www.ncbi.nlm.nih.gov/pubmed/16401726
http://dx.doi.org/10.1083/jcb.200507149