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Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis

The anthrax toxin is composed of three independent polypeptide chains. Successful intoxication only occurs when heptamerization of the receptor-binding polypeptide, the protective antigen (PA), allows binding of the two enzymatic subunits before endocytosis. We show that this tailored behavior is ca...

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Detalles Bibliográficos
Autores principales: Abrami, Laurence, Leppla, Stephen H., van der Goot, F. Gisou
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063559/
https://www.ncbi.nlm.nih.gov/pubmed/16401723
http://dx.doi.org/10.1083/jcb.200507067