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Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis
The anthrax toxin is composed of three independent polypeptide chains. Successful intoxication only occurs when heptamerization of the receptor-binding polypeptide, the protective antigen (PA), allows binding of the two enzymatic subunits before endocytosis. We show that this tailored behavior is ca...
Autores principales: | Abrami, Laurence, Leppla, Stephen H., van der Goot, F. Gisou |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063559/ https://www.ncbi.nlm.nih.gov/pubmed/16401723 http://dx.doi.org/10.1083/jcb.200507067 |
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