Spatial targeting of type II protein kinase A to filopodia mediates the regulation of growth cone guidance by cAMP

The second messenger cyclic adenosine monophosphate (cAMP) plays a pivotal role in axonal growth and guidance, but its downstream mechanisms remain elusive. In this study, we report that type II protein kinase A (PKA) is highly enriched in growth cone filopodia, and this spatial localization enables...

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Detalles Bibliográficos
Autores principales: Han, Jianzhong, Han, Liang, Tiwari, Priyanka, Wen, Zhexing, Zheng, James Q.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063631/
https://www.ncbi.nlm.nih.gov/pubmed/17200417
http://dx.doi.org/10.1083/jcb.200607128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063631/
https://www.ncbi.nlm.nih.gov/pubmed/17200417
http://dx.doi.org/10.1083/jcb.200607128

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