A novel GTPase, CRAG, mediates promyelocytic leukemia protein–associated nuclear body formation and degradation of expanded polyglutamine protein

Polyglutamine diseases are inherited neurodegenerative diseases caused by the expanded polyglutamine proteins (polyQs). We have identified a novel guanosine triphosphatase (GTPase) named CRAG that contains a nuclear localization signal (NLS) sequence and forms nuclear inclusions in response to stres...

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Detalles Bibliográficos
Autores principales: Qin, Qingyu, Inatome, Ryoko, Hotta, Azusa, Kojima, Masaki, Yamamura, Hirohei, Hirai, Hirokazu, Yoshizawa, Toshihiro, Tanaka, Hirofumi, Fukami, Kiyoko, Yanagi, Shigeru
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063670/
https://www.ncbi.nlm.nih.gov/pubmed/16461359
http://dx.doi.org/10.1083/jcb.200505079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063670/
https://www.ncbi.nlm.nih.gov/pubmed/16461359
http://dx.doi.org/10.1083/jcb.200505079

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