Early aging–associated phenotypes in Bub3/Rae1 haploinsufficient mice

Aging is a highly complex biological process that is believed to involve multiple mechanisms. Mice that have small amounts of the mitotic checkpoint protein BubR1 age much faster than normal mice, but whether other mitotic checkpoint genes function to prevent the early onset of aging is unknown. In...

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Detalles Bibliográficos
Autores principales: Baker, Darren J., Jeganathan, Karthik B., Malureanu, Liviu, Perez-Terzic, Carmen, Terzic, Andre, van Deursen, Jan M.A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063673/
https://www.ncbi.nlm.nih.gov/pubmed/16476774
http://dx.doi.org/10.1083/jcb.200507081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063673/
https://www.ncbi.nlm.nih.gov/pubmed/16476774
http://dx.doi.org/10.1083/jcb.200507081

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