pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response

Upon the accumulation of unfolded proteins in the mammalian endoplasmic reticulum (ER), X-box binding protein 1 (XBP1) premessenger RNA (premRNA) is converted to mature mRNA by unconventional splicing that is mediated by the endonuclease inositol-requiring enzyme 1. The transcription factor protein...

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Detalles Bibliográficos
Autores principales: Yoshida, Hiderou, Oku, Masaya, Suzuki, Mie, Mori, Kazutoshi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063676/
https://www.ncbi.nlm.nih.gov/pubmed/16461360
http://dx.doi.org/10.1083/jcb.200508145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063676/
https://www.ncbi.nlm.nih.gov/pubmed/16461360
http://dx.doi.org/10.1083/jcb.200508145

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