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Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73

Transcriptional disturbance is implicated in the pathology of polyglutamine diseases, including Huntington's disease (HD). However, it is unknown whether transcriptional repression leads to neuronal death or what forms that death might take. We found transcriptional repression-induced atypical...

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Detalles Bibliográficos
Autores principales: Hoshino, Masataka, Qi, Mei-ling, Yoshimura, Natsue, Miyashita, Tomoyuki, Tagawa, Kazuhiko, Wada, Yo-ichi, Enokido, Yasushi, Marubuchi, Shigeki, Harjes, Phoebe, Arai, Nobutaka, Oyanagi, Kiyomitsu, Blandino, Giovanni, Sudol, Marius, Rich, Tina, Kanazawa, Ichiro, Wanker, Erich E., Saitoe, Minoru, Okazawa, Hitoshi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063678/
https://www.ncbi.nlm.nih.gov/pubmed/16461361
http://dx.doi.org/10.1083/jcb.200509132