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Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly
The polarity protein Par-3 plays critical roles in axon specification and the establishment of epithelial apico-basal polarity. Par-3 associates with Par-6 and atypical protein kinase C and is required for the proper assembly of tight junctions, but the molecular basis for its functions is poorly un...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063700/ https://www.ncbi.nlm.nih.gov/pubmed/16505165 http://dx.doi.org/10.1083/jcb.200510061 |