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Targeting and activation of Rac1 are mediated by the exchange factor β-Pix

Rho guanosine triphosphatases (GTPases) are critical regulators of cytoskeletal dynamics and control complex functions such as cell adhesion, spreading, migration, and cell division. It is generally accepted that localized GTPase activation is required for the proper initiation of downstream signali...

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Detalles Bibliográficos
Autores principales: ten Klooster, Jean Paul, Jaffer, Zahara M., Chernoff, Jonathan, Hordijk, Peter L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063707/
https://www.ncbi.nlm.nih.gov/pubmed/16492808
http://dx.doi.org/10.1083/jcb.200509096