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A Maurer's cleft–associated protein is essential for expression of the major malaria virulence antigen on the surface of infected red blood cells
The high mortality of Plasmodium falciparum malaria is the result of a parasite ligand, PfEMP1 (P. falciparum) erythrocyte membrane protein 1), on the surface of infected red blood cells (IRBCs), which adheres to the vascular endothelium and causes the sequestration of IRBCs in the microvasculature....
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063733/ https://www.ncbi.nlm.nih.gov/pubmed/16520384 http://dx.doi.org/10.1083/jcb.200509122 |