Cargando…

A Maurer's cleft–associated protein is essential for expression of the major malaria virulence antigen on the surface of infected red blood cells

The high mortality of Plasmodium falciparum malaria is the result of a parasite ligand, PfEMP1 (P. falciparum) erythrocyte membrane protein 1), on the surface of infected red blood cells (IRBCs), which adheres to the vascular endothelium and causes the sequestration of IRBCs in the microvasculature....

Descripción completa

Detalles Bibliográficos
Autores principales: Cooke, Brian M., Buckingham, Donna W., Glenister, Fiona K., Fernandez, Kate M., Bannister, Lawrence H., Marti, Matthias, Mohandas, Narla, Coppel, Ross L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063733/
https://www.ncbi.nlm.nih.gov/pubmed/16520384
http://dx.doi.org/10.1083/jcb.200509122