Two distinct cytoplasmic regions of the β(2) integrin chain regulate RhoA function during phagocytosis

α(M)β(2) integrins mediate phagocytosis of opsonized particles in a process controlled by RhoA, Rho kinase, myosin II, Arp2/3, and actin polymerization. α(M)β(2), Rho, Arp2/3, and F-actin accumulate underneath bound particles; however, the mechanism regulating Rho function during α(M)β(2)-mediated p...

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Detalles Bibliográficos
Autores principales: Wiedemann, Agnès, Patel, Jayesh C., Lim, Jenson, Tsun, Andy, van Kooyk, Yvette, Caron, Emmanuelle
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063764/
https://www.ncbi.nlm.nih.gov/pubmed/16567504
http://dx.doi.org/10.1083/jcb.200508075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063764/
https://www.ncbi.nlm.nih.gov/pubmed/16567504
http://dx.doi.org/10.1083/jcb.200508075

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