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Two distinct cytoplasmic regions of the β(2) integrin chain regulate RhoA function during phagocytosis
α(M)β(2) integrins mediate phagocytosis of opsonized particles in a process controlled by RhoA, Rho kinase, myosin II, Arp2/3, and actin polymerization. α(M)β(2), Rho, Arp2/3, and F-actin accumulate underneath bound particles; however, the mechanism regulating Rho function during α(M)β(2)-mediated p...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063764/ https://www.ncbi.nlm.nih.gov/pubmed/16567504 http://dx.doi.org/10.1083/jcb.200508075 |