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Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors

It is commonly assumed that photoreceptor (PR) outer segment (OS) morphogenesis is reliant upon the presence of peripherin/rds, hereafter termed Rds. In this study, we demonstrate a differential requirement of Rds during rod and cone OS morphogenesis. In the absence of this PR-specific protein, rods...

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Detalles Bibliográficos
Autores principales: Farjo, Rafal, Skaggs, Jeff S., Nagel, Barbara A., Quiambao, Alexander B., Nash, Zack A., Fliesler, Steven J., Naash, Muna I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063789/
https://www.ncbi.nlm.nih.gov/pubmed/16585269
http://dx.doi.org/10.1083/jcb.200509036