Cargando…

Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling

TopBP1-like proteins, which include Xenopus laevis Xmus101, are required for DNA replication and have been linked to replication checkpoint control. A direct role for TopBP1/Mus101 in checkpoint control has been difficult to prove, however, because of the requirement for replication in generating th...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Shan, Lindsay, Howard D., Michael, W. Matthew
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063809/
https://www.ncbi.nlm.nih.gov/pubmed/16618813
http://dx.doi.org/10.1083/jcb.200601076