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Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling

TopBP1-like proteins, which include Xenopus laevis Xmus101, are required for DNA replication and have been linked to replication checkpoint control. A direct role for TopBP1/Mus101 in checkpoint control has been difficult to prove, however, because of the requirement for replication in generating th...

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Detalles Bibliográficos
Autores principales:	Yan, Shan, Lindsay, Howard D., Michael, W. Matthew
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063809/ https://www.ncbi.nlm.nih.gov/pubmed/16618813 http://dx.doi.org/10.1083/jcb.200601076

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