Drosophila melanogaster auxilin regulates the internalization of Delta to control activity of the Notch signaling pathway

We have isolated mutations in the Drosophila melanogaster homologue of auxilin, a J-domain–containing protein known to cooperate with Hsc70 in the disassembly of clathrin coats from clathrin-coated vesicles in vitro. Consistent with this biochemical role, animals with reduced auxilin function exhibi...

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Detalles Bibliográficos
Autores principales: Hagedorn, Elliott J., Bayraktar, Jennifer L., Kandachar, Vasundhara R., Bai, Ting, Englert, Dane M., Chang, Henry C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063844/
https://www.ncbi.nlm.nih.gov/pubmed/16682530
http://dx.doi.org/10.1083/jcb.200602054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063844/
https://www.ncbi.nlm.nih.gov/pubmed/16682530
http://dx.doi.org/10.1083/jcb.200602054

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