Cargando…
Structural damage to meiotic chromosomes impairs DNA recombination and checkpoint control in mammalian oocytes
Meiosis in human oocytes is a highly error-prone process with profound effects on germ cell and embryo development. The synaptonemal complex protein 3 (SYCP3) transiently supports the structural organization of the meiotic chromosome axis. Offspring derived from murine Sycp3 (−) (/) (−) females die...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063859/ https://www.ncbi.nlm.nih.gov/pubmed/16717125 http://dx.doi.org/10.1083/jcb.200512077 |