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Semaphorin 4D/Plexin-B1–mediated R-Ras GAP activity inhibits cell migration by regulating β(1) integrin activity

Plexins are cell surface receptors for semaphorins and regulate cell migration in many cell types. We recently reported that the semaphorin 4D (Sema4D) receptor Plexin-B1 functions as a GTPase-activating protein (GAP) for R-Ras, a member of Ras family GTPases implicated in regulation of integrin act...

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Detalles Bibliográficos
Autores principales: Oinuma, Izumi, Katoh, Hironori, Negishi, Manabu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063868/
https://www.ncbi.nlm.nih.gov/pubmed/16702230
http://dx.doi.org/10.1083/jcb.200508204