Excess Mcm2–7 license dormant origins of replication that can be used under conditions of replicative stress

In late mitosis and early G1, replication origins are licensed for subsequent use by loading complexes of the minichromosome maintenance proteins 2–7 (Mcm2–7). The number of Mcm2–7 complexes loaded onto DNA greatly exceeds the number of replication origins used during S phase, but the function of th...

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Detalles Bibliográficos
Autores principales: Woodward, Anna M., Göhler, Thomas, Luciani, M. Gloria, Oehlmann, Maren, Ge, Xinquan, Gartner, Anton, Jackson, Dean A., Blow, J. Julian
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063885/
https://www.ncbi.nlm.nih.gov/pubmed/16754955
http://dx.doi.org/10.1083/jcb.200602108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063885/
https://www.ncbi.nlm.nih.gov/pubmed/16754955
http://dx.doi.org/10.1083/jcb.200602108

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