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Protein disulfide isomerase–like proteins play opposing roles during retrotranslocation

Misfolded proteins in the endoplasmic reticulum (ER) are retained in the organelle or retrotranslocated to the cytosol for proteasomal degradation. ER chaperones that guide these opposing processes are largely unknown. We developed a semipermeabilized cell system to study the retrotranslocation of c...

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Detalles Bibliográficos
Autores principales: Forster, Michele L., Sivick, Kelsey, Park, Young-nam, Arvan, Peter, Lencer, Wayne I., Tsai, Billy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063911/
https://www.ncbi.nlm.nih.gov/pubmed/16785320
http://dx.doi.org/10.1083/jcb.200602046