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Apical targeting of syntaxin 3 is essential for epithelial cell polarity

In polarized epithelial cells, syntaxin 3 localizes to the apical plasma membrane and is involved in membrane fusion of apical trafficking pathways. We show that syntaxin 3 contains a necessary and sufficient apical targeting signal centered around a conserved FMDE motif. Mutation of any of three cr...

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Detalles Bibliográficos
Autores principales: Sharma, Nikunj, Low, Seng Hui, Misra, Saurav, Pallavi, Bhattaram, Weimbs, Thomas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063918/
https://www.ncbi.nlm.nih.gov/pubmed/16785322
http://dx.doi.org/10.1083/jcb.200603132