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Apical targeting of syntaxin 3 is essential for epithelial cell polarity
In polarized epithelial cells, syntaxin 3 localizes to the apical plasma membrane and is involved in membrane fusion of apical trafficking pathways. We show that syntaxin 3 contains a necessary and sufficient apical targeting signal centered around a conserved FMDE motif. Mutation of any of three cr...
Autores principales: | Sharma, Nikunj, Low, Seng Hui, Misra, Saurav, Pallavi, Bhattaram, Weimbs, Thomas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063918/ https://www.ncbi.nlm.nih.gov/pubmed/16785322 http://dx.doi.org/10.1083/jcb.200603132 |
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