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The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans

Polarized intracellular trafficking in epithelia is critical in development, immunity, and physiology to deliver morphogens, defensins, or ion pumps to the appropriate membrane domain. The mechanisms that control apical trafficking remain poorly defined. Using Caenorhabditis elegans, we characterize...

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Detalles Bibliográficos
Autores principales: Liégeois, Samuel, Benedetto, Alexandre, Garnier, Jean-Marie, Schwab, Yannick, Labouesse, Michel
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063919/
https://www.ncbi.nlm.nih.gov/pubmed/16785323
http://dx.doi.org/10.1083/jcb.200511072