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Structural basis for tetraspanin functions as revealed by the cryo-EM structure of uroplakin complexes at 6-Å resolution

Tetraspanin uroplakins (UPs) Ia and Ib, together with their single-spanning transmembrane protein partners UP II and IIIa, form a unique crystalline 2D array of 16-nm particles covering almost the entire urothelial surface. A 6 Å–resolution cryo-EM structure of the UP particle revealed that the UP t...

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Detalles Bibliográficos
Autores principales: Min, Guangwei, Wang, Huaibin, Sun, Tung-Tien, Kong, Xiang-Peng
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063921/
https://www.ncbi.nlm.nih.gov/pubmed/16785325
http://dx.doi.org/10.1083/jcb.200602086