Nucleoplasmic LAP2α–lamin A complexes are required to maintain a proliferative state in human fibroblasts

In human diploid fibroblasts (HDFs), expression of lamina-associated polypeptide 2 α (LAP2α) upon entry and exit from G(0) is tightly correlated with phosphorylation and subnuclear localization of retinoblastoma protein (Rb). Phosphoisoforms of Rb and LAP2α are down-regulated in G(0). Although RbS78...

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Detalles Bibliográficos
Autores principales: Pekovic, Vanja, Harborth, Jens, Broers, Jos L.V., Ramaekers, Frans C.S., van Engelen, Baziel, Lammens, Martin, von Zglinicki, Thomas, Foisner, Roland, Hutchison, Chris, Markiewicz, Ewa
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063936/
https://www.ncbi.nlm.nih.gov/pubmed/17227891
http://dx.doi.org/10.1083/jcb.200606139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063936/
https://www.ncbi.nlm.nih.gov/pubmed/17227891
http://dx.doi.org/10.1083/jcb.200606139

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