Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells

How centrosome removal or perturbations of centrosomal proteins leads to G1 arrest in untransformed mammalian cells has been a mystery. We use microsurgery and laser ablation to remove the centrosome from two types of normal human cells. First, we find that the cells assemble centrioles de novo afte...

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Detalles Bibliográficos
Autores principales: Uetake, Yumi, Lončarek, Jadranka, Nordberg, Joshua J., English, Christopher N., La Terra, Sabrina, Khodjakov, Alexey, Sluder, Greenfield
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063937/
https://www.ncbi.nlm.nih.gov/pubmed/17227892
http://dx.doi.org/10.1083/jcb.200607073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063937/
https://www.ncbi.nlm.nih.gov/pubmed/17227892
http://dx.doi.org/10.1083/jcb.200607073

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