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Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells
How centrosome removal or perturbations of centrosomal proteins leads to G1 arrest in untransformed mammalian cells has been a mystery. We use microsurgery and laser ablation to remove the centrosome from two types of normal human cells. First, we find that the cells assemble centrioles de novo afte...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063937/ https://www.ncbi.nlm.nih.gov/pubmed/17227892 http://dx.doi.org/10.1083/jcb.200607073 |