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Axons break in animals lacking β-spectrin

Axons and dendrites can withstand acute mechanical strain despite their small diameter. In this study, we demonstrate that β-spectrin is required for the physical integrity of neuronal processes in the nematode Caenorhabditis elegans. Axons in β-spectrin mutants spontaneously break. Breakage is caus...

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Detalles Bibliográficos
Autores principales: Hammarlund, Marc, Jorgensen, Erik M., Bastiani, Michael J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063953/
https://www.ncbi.nlm.nih.gov/pubmed/17261846
http://dx.doi.org/10.1083/jcb.200611117