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Type Iγ phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with μ1B adaptin

Assembly of E-cadherin–based adherens junctions (AJ) is obligatory for establishment of polarized epithelia and plays a key role in repressing the invasiveness of many carcinomas. Here we show that type Iγ phosphatidylinositol phosphate kinase (PIPKIγ) directly binds to E-cadherin and modulates E-ca...

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Detalles Bibliográficos
Autores principales: Ling, Kun, Bairstow, Shawn F., Carbonara, Chateen, Turbin, Dmitry A., Huntsman, David G., Anderson, Richard A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063960/
https://www.ncbi.nlm.nih.gov/pubmed/17261850
http://dx.doi.org/10.1083/jcb.200606023