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Hyaluronan and CD44 antagonize mitogen-dependent cyclin D1 expression in mesenchymal cells

High molecular weight (HMW) hyaluronan (HA) is widely distributed in the extracellular matrix, but its biological activities remain incompletely understood. We previously reported that HMW-HA binding to CD44 antagonizes mitogen-induced S-phase entry in vascular smooth muscle cells (SMCs; Cuff, C.A.,...

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Detalles Bibliográficos
Autores principales: Kothapalli, Devashish, Zhao, Liang, Hawthorne, Elizabeth A., Cheng, Yan, Lee, Eric, Puré, Ellen, Assoian, Richard K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063987/
https://www.ncbi.nlm.nih.gov/pubmed/17296798
http://dx.doi.org/10.1083/jcb.200611058