Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression

Radial organization of nuclei with peripheral gene-poor chromosomes and central gene-rich chromosomes is common and could depend on the nuclear boundary as a scaffold or position marker. To test this, we studied the role of the ubiquitous nuclear envelope (NE) component lamin B1 in NE stability, chr...

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Detalles Bibliográficos
Autores principales: Malhas, Ashraf, Lee, Chiu Fan, Sanders, Rebecca, Saunders, Nigel J., Vaux, David J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064018/
https://www.ncbi.nlm.nih.gov/pubmed/17312019
http://dx.doi.org/10.1083/jcb.200607054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064018/
https://www.ncbi.nlm.nih.gov/pubmed/17312019
http://dx.doi.org/10.1083/jcb.200607054

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