Cargando…

Membrane chaperone Shr3 assists in folding amino acid permeases preventing precocious ERAD

The yeast endoplasmic reticulum (ER) membrane-localized chaperone Shr3 plays a critical role in enabling amino acid permeases (AAPs) to fold and attain proper structures required for functional expression at the plasma membrane. In the absence of Shr3, AAPs specifically accumulate in the ER, where d...

Descripción completa

Detalles Bibliográficos
Autores principales: Kota, Jhansi, Gilstring, C. Fredrik, Ljungdahl, Per O.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064020/
https://www.ncbi.nlm.nih.gov/pubmed/17325204
http://dx.doi.org/10.1083/jcb.200612100