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Membrane chaperone Shr3 assists in folding amino acid permeases preventing precocious ERAD
The yeast endoplasmic reticulum (ER) membrane-localized chaperone Shr3 plays a critical role in enabling amino acid permeases (AAPs) to fold and attain proper structures required for functional expression at the plasma membrane. In the absence of Shr3, AAPs specifically accumulate in the ER, where d...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064020/ https://www.ncbi.nlm.nih.gov/pubmed/17325204 http://dx.doi.org/10.1083/jcb.200612100 |