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Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics

In response to αβ1 integrin signaling, transducers such as focal adhesion kinase (FAK) become activated, relaying to specific machineries and triggering distinct cellular responses. By conditionally ablating Fak in skin epidermis and culturing Fak-null keratinocytes, we show that FAK is dispensable...

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Detalles Bibliográficos
Autores principales: Schober, Markus, Raghavan, Srikala, Nikolova, Maria, Polak, Lisa, Pasolli, H. Amalia, Beggs, Hilary E., Reichardt, Louis F., Fuchs, Elaine
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064024/
https://www.ncbi.nlm.nih.gov/pubmed/17325207
http://dx.doi.org/10.1083/jcb.200608010