Cargando…
Identification of prothymosin-α1, the necrosis–apoptosis switch molecule in cortical neuronal cultures
We initially identified a nuclear protein, prothymosin-α1 (ProTα), as a key protein inhibiting necrosis by subjecting conditioned media from serum-free cultures of cortical neurons to a few chromatography steps. ProTα inhibited necrosis of cultured neurons by preventing rapid loss of cellular adenos...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064059/ https://www.ncbi.nlm.nih.gov/pubmed/17353361 http://dx.doi.org/10.1083/jcb.200608022 |