Cargando…

The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization

Cell polarization is required for virtually all functions of T cells, including transendothelial migration in response to chemokines. However, the molecular pathways that establish T cell polarity are poorly understood. We show that the activation of the partitioning defective (Par) polarity complex...

Descripción completa

Detalles Bibliográficos
Autores principales: Gérard, Audrey, Mertens, Alexander E.E., van der Kammen, Rob A., Collard, John G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064060/
https://www.ncbi.nlm.nih.gov/pubmed/17353362
http://dx.doi.org/10.1083/jcb.200608161