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Pseudomonas aeruginosa exploits a PIP3-dependent pathway to transform apical into basolateral membrane

Pseudomonas aeruginosa, an important human pathogen, preferentially binds and enters injured cells from the basolateral (BL) surface. We previously demonstrated that activation of phosphatidylinositol 3-kinase (PI3K) and Akt are necessary and sufficient for P. aeruginosa entry from the apical (AP) s...

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Detalles Bibliográficos
Autores principales: Kierbel, Arlinet, Gassama-Diagne, Ama, Rocha, Claudia, Radoshevich, Lilliana, Olson, Joan, Mostov, Keith, Engel, Joanne
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064102/
https://www.ncbi.nlm.nih.gov/pubmed/17403925
http://dx.doi.org/10.1083/jcb.200605142