The ubiquitin E3 ligase POSH regulates calcium homeostasis through spatial control of Herp

The ubiquitin (Ub) domain protein Herp plays a crucial role in the maintenance of calcium homeostasis during endoplasmic reticulum (ER) stress. We now show that Herp is a substrate as well as an activator of the E3 Ub ligase POSH. Herp-mediated POSH activation requires the Ubl domain and exclusively...

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Detalles Bibliográficos
Autores principales: Tuvia, Shmuel, Taglicht, Daniel, Erez, Omri, Alroy, Iris, Alchanati, Iris, Bicoviski, Vivian, Dori-Bachash, Mally, Ben-Avraham, Danny, Reiss, Yuval
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064109/
https://www.ncbi.nlm.nih.gov/pubmed/17420289
http://dx.doi.org/10.1083/jcb.200611036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064109/
https://www.ncbi.nlm.nih.gov/pubmed/17420289
http://dx.doi.org/10.1083/jcb.200611036

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