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Compartmentalization of androgen receptor protein–protein interactions in living cells

Steroid receptors regulate gene expression in a ligand-dependent manner by binding specific DNA sequences. Ligand binding also changes the conformation of the ligand binding domain (LBD), allowing interaction with coregulators via LxxLL motifs. Androgen receptors (ARs) preferentially interact with c...

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Detalles Bibliográficos
Autores principales: van Royen, Martin E., Cunha, Sónia M., Brink, Maartje C., Mattern, Karin A., Nigg, Alex L., Dubbink, Hendrikus J., Verschure, Pernette J., Trapman, Jan, Houtsmuller, Adriaan B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064112/
https://www.ncbi.nlm.nih.gov/pubmed/17420290
http://dx.doi.org/10.1083/jcb.200609178