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Compartmentalization of androgen receptor protein–protein interactions in living cells
Steroid receptors regulate gene expression in a ligand-dependent manner by binding specific DNA sequences. Ligand binding also changes the conformation of the ligand binding domain (LBD), allowing interaction with coregulators via LxxLL motifs. Androgen receptors (ARs) preferentially interact with c...
Autores principales: | van Royen, Martin E., Cunha, Sónia M., Brink, Maartje C., Mattern, Karin A., Nigg, Alex L., Dubbink, Hendrikus J., Verschure, Pernette J., Trapman, Jan, Houtsmuller, Adriaan B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064112/ https://www.ncbi.nlm.nih.gov/pubmed/17420290 http://dx.doi.org/10.1083/jcb.200609178 |
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