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Myosin VI is required for sorting of AP-1B–dependent cargo to the basolateral domain in polarized MDCK cells

In polarized epithelial cells, newly synthesized membrane proteins are delivered on specific pathways to either the apical or basolateral domains, depending on the sorting motifs present in these proteins. Because myosin VI has been shown to facilitate secretory traffic in nonpolarized cells, we inv...

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Detalles Bibliográficos
Autores principales: Au, Josephine Sui-Yan, Puri, Claudia, Ihrke, Gudrun, Kendrick-Jones, John, Buss, Folma
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064115/
https://www.ncbi.nlm.nih.gov/pubmed/17403927
http://dx.doi.org/10.1083/jcb.200608126