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12R-lipoxygenase deficiency disrupts epidermal barrier function

12R-lipoxygenase (12R-LOX) and the epidermal LOX-3 (eLOX-3) constitute a novel LOX pathway involved in terminal differentiation in skin. This view is supported by recent studies showing that inactivating mutations in 12R-LOX and eLOX-3 are linked to the development of autosomal recessive congenital...

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Detalles Bibliográficos
Autores principales: Epp, Nikolas, Fürstenberger, Gerhard, Müller, Karsten, de Juanes, Silvia, Leitges, Michael, Hausser, Ingrid, Thieme, Florian, Liebisch, Gerhard, Schmitz, Gerd, Krieg, Peter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064121/
https://www.ncbi.nlm.nih.gov/pubmed/17403930
http://dx.doi.org/10.1083/jcb.200612116