Cargando…

Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence

Specific mammalian genes functionally and dynamically associate together within the nucleus. Yet, how an array of many genes along the chromosome sequence can be spatially organized and folded together is unknown. We investigated the 3D structure of a well-annotated, highly conserved 4.3-Mb region o...

Descripción completa

Detalles Bibliográficos
Autores principales: Shopland, Lindsay S., Lynch, Christopher R., Peterson, Kevin A., Thornton, Kathleen, Kepper, Nick, von Hase, Johann, Stein, Stefan, Vincent, Sarah, Molloy, Kelly R., Kreth, Gregor, Cremer, Christoph, Bult, Carol J., O'Brien, Timothy P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064156/
https://www.ncbi.nlm.nih.gov/pubmed/16818717
http://dx.doi.org/10.1083/jcb.200603083