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Uncoupling global and fine-tuning replication timing determinants for mouse pericentric heterochromatin

Mouse chromocenters are clusters of late-replicating pericentric heterochromatin containing HP1 bound to trimethylated lysine 9 of histone H3 (Me(3)K9H3). Using a cell-free system to initiate replication within G1-phase nuclei, we demonstrate that chromocenters acquire the property of late replicati...

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Detalles Bibliográficos
Autores principales: Wu, Rong, Singh, Prim B., Gilbert, David M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064179/
https://www.ncbi.nlm.nih.gov/pubmed/16831888
http://dx.doi.org/10.1083/jcb.200601113